https://www.ceesdekker.net - An Overview

https://www.ceesdekker.net - An Overview

Blog Article

‘Of course, that may be about proper. I search for a Actual physical comprehension of Organic methods in a very bottom-up way. I believe you could potentially distinguish three traces of investigate in my group at this time. The initial problems chromosome construction: How will you get a metre-long DNA polymer folded and organised in this kind of microscopic mobile? We've got created visualisation approaches that allow us to study how, one example is, SMC proteins loop DNA (video on Youtube) as a way to Develop up chromosomes.

This problem is for tests whether or not you are a human customer and to prevent automated spam submissions.

‘It had been just a make a difference of picking up a reserve on mobile biology and starting to study. I'd come from a globe of extremely-significant vacuums, cryostats and quantum phenomena, and now I used to be Operating at home temperature with molecular biology kits.

Sculpting nano-electrodes with a transmission electron beam for electrical and geometrical characterization of nanoparticles.

2010, produced a different way (‘wedging transfer’) to govern nanostructures; first report of DNA translocation by means of graphene nanopores; and recognized hybrid nanopores by directed insertion of α-hemolysin into sound-point out nanopores

SMC complexes can go Actual physical roadblocks larger than their ring measurement, indicating a nontopological mechanism for DNA loop extrusion

We use nanofabricated microfluidic buildings to sample spatial boundaries for micro organism and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement with the molecular and cellular degree. Our tasks contain the following:

Dynamic ParB–DNA interactions initiate and preserve a partition condensate for bacterial chromosome segregation

‘Of course, I realize people have been amazed at enough time. At the conclusion of the nineties, After i was in my forties, I https://www.ceesdekker.net was Professor of Molecular Electronics and I have to confess that it experienced become a bit bored, I didn’t master Significantly anymore. The field went far more into the application side, how you could potentially combine nanotubes into Digital circuits.

There was 1 difficulty however — we didn't notice any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule stage, conducting polymers ended up basically not such fantastic conductors, which was fairly disappointing. We Hence broadened our look at to test to seek out additional promising molecules.

An integrated microfluidic platform for quantifying drug permeation throughout biomimetic vesicle membranes

2006, to start with demonstration of molecular sorting inside a lab over a chip applying biomotors; discovery of nanobubbles in strong-condition nanopores; and to start with estimate of electrokinetic Power conversion in the nanofluidic channel

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes

‘I'm pushed by question and queries. On a fabric stage I obtain responses in physics, but I experience my deepest joy with God. That faith also drives my science And the way I take care of persons.